Ketamine and Spravato Treatment in Missouri

Based on published pricing and coverage rules as of 2019-03-05. Sources for every figure this tool can show:

Only esketamine (Spravato) is FDA-approved to treat depression. Racemic ketamine given by IV, injection, or under the tongue has no FDA approval for any psychiatric condition and is used off-label — that is, an approved drug used for an unapproved purpose. as of 30 Apr 2025 · U.S. Food and Drug Administration (source 1, opens in a new tab)

Under Original Medicare Part B in 2026 you pay a $283 yearly deductible first, and after that you generally pay 20% of the Medicare-approved amount for covered services. as of 1 Jan 2026 · Centers for Medicare and Medicaid Services (source 2, opens in a new tab)Deductible and premium amounts are set annually and change each January.

MO HealthNet, Missouri's Medicaid programme, covers Spravato but applies a clinical edit requiring prior approval, and the medicine must be given at a treatment centre certified in the Spravato REMS programme. as of 21 Jul 2022 · Missouri Department of Social Services, MO HealthNet Division (source 4, opens in a new tab)The published criteria document dates from 2022 and a newer revision may exist that we could not retrieve. Ask your clinic to confirm the current requirements before you rely on these details.

Best available information: We could not source a Missouri-specific price for intramuscular ketamine. Secondary directories put it somewhere around $300 to $600 an injection. as of 26 Apr 2026 · HealingMaps (source 7, opens in a new tab)No Missouri clinic price sheet supports this band. It is a directory estimate, not a Missouri figure.

Best available information: Missouri clinics very rarely publish what they charge for IV ketamine. Regional figures put a single infusion somewhere around $350 to $800, but we could not find a single Missouri clinic publishing an infusion price, so treat this as a rough regional guide only. as of 26 Apr 2026 · HealingMaps (source 8, opens in a new tab)Of nine Missouri clinic websites checked, eight publish no prices at all. Every Kansas City clinic we found with a published infusion price is physically in Kansas, not Missouri. You will have to phone to get a real number — our cost checklist lists the questions that get you one.

In Missouri, sublingual ketamine troches themselves cost only a few dollars each. The supervised session around them is what costs money — one St. Louis practice publishes roughly $225 for a preparation or integration appointment and around $790 for a two-and-a-half-hour dosing session. At-home telehealth programmes serving Missouri start at roughly $165 a session. as of 18 Jul 2026 · Alternative Therapy STL (source 9, opens in a new tab)This is the only Missouri clinic we found publishing any prices at all, and it offers only sublingual treatment. The medicine and the session are billed separately — ask which a quoted price covers.

Best available information: No Missouri clinic we could find publishes a self-pay price for Spravato. National figures suggest roughly $850 to $1,600 a session covering both the medicine and the required two-hour monitoring, but we have no Missouri figure we would stand behind. as of 5 May 2026 · HealingMaps (source 10, opens in a new tab)This is a national figure from one secondary directory, not a Missouri price. Our estimator does not produce a self-pay Spravato number from it.

The FDA approved Spravato (esketamine) nasal spray on 5 March 2019, for use with an oral antidepressant, for adults with treatment-resistant depression. as of 5 Mar 2019 · U.S. Food and Drug Administration (source 13, opens in a new tab)

Spravato is available only through a restricted safety programme called a Risk Evaluation and Mitigation Strategy (REMS), and may only be given in a certified healthcare setting under a provider's direct observation. Patients never take it home. as of 30 Apr 2025 · U.S. Food and Drug Administration (source 16, opens in a new tab)

Best available information: Spravato's list price is not published by the manufacturer or in any free public source. At launch in 2019 the wholesale acquisition cost was around $590 for a 56 mg dose and $885 for an 84 mg dose, and the current list price is very likely higher. as of 5 Mar 2019 · Drugs.com (source 17, opens in a new tab)Wholesale acquisition cost is published only in paywalled pricing compendia. The figures here are seven years old and come from a secondary source, so we do not use them to produce a dollar estimate — the estimator suppresses Spravato cash figures rather than presenting a number this weak.

The Spravato withMe savings programme is not available to anyone using a state or federal government health programme, including Medicare, Medicaid, TRICARE, the Department of Defense, and the Veterans Administration. as of 18 Jul 2026 · Johnson & Johnson (source 18, opens in a new tab)

Through the Spravato withMe savings programme, eligible patients with commercial insurance may pay as little as $10 per treatment for the medicine itself, subject to yearly maximum benefits and quantity limits. as of 18 Jul 2026 · Johnson & Johnson (source 19, opens in a new tab)The programme covers the medicine, not the office visit or the two-hour observation, which is often the larger share of the bill. The official terms state that a yearly maximum applies but do not publish the amount, so we do not either. Terms are set per calendar year.